After the tragic deaths of her husband and daughter, Sarah Doyle moves back to her childhood home with her estranged brother, Richard. It's not long before Sarah begins to experience supernatural phenomena of a violent and hostile nature. Bewildered and desperate, Richard enlists the aid of a paranormal investigator who confirms that Sarah has become possessed by a powerful demon. Together, the three men will go to battle to save Sarah's soul.
Special Agent Alexander Connor is sent to investigate a house, from which a woman named Sandra has made numerous 911 calls. Things become more complicated than expected for Agent Connor, as he finds he must also rescue a police officer who responded to the home 24 hours earlier. Soon, Agent Connor will discover a horrifying secret; that Sandra is one of LUMEN CORPORATION's donors and has devoted her house to the corporation; a house which has been turned into a research lab for atrocious experiments performed on human beings.