Two hundred years after Mary Shelley's novel the brilliant but mad Doctor (Thomas Kretschmann) has sustained his creature and himself over two centuries through genetic experimentation. In present-day America Detective O'Connor (Parker Posey) is investigating a series of horrific murders which leads her to the doctor and his creature. What she uncovers reveals the strange evolution the doctor and his creation undergo over the course of two centuries and the divergent paths creator and monster take in pursuing good or evil. 在玛丽·雪莱的小说两百年后，才华横溢但疯狂的医生使他自己和他的怪物从两个世纪前的当初的实验一直幸存下来。如今，美国探员 O'Connor 在调查系列谋杀案时，被引向了医生和他的怪物，并揭露出在长达两个多世纪的漫长岁月中，医生和他作品间的奇特演变和他们踏上善与恶的不同道路。
In Italy, old, dirty, congested prisons full of violence and abuse are a dim and distant memory. Now prisoners serve their sentences in a state of deep sleep which renders them inoffensive and has drastically reduced reoffending rates. Hypersleep is an efficient, economically viable and reliable system. That is, until the day when David Damiani (Stefano Accorsi), a psychologist charged with monitoring prisoners’ mental states, finds himself faced with a prisoner about whom all information has been lost. It’s an unexpected event which triggers a chain of unforeseeable event, forcing David to face up to the ghosts of his very own past.
Four men working at a remote scientific outpost unravel the disturbing secrets about the facility's history, signaling the approach of a mysterious menace that will not only consume these men, but, perhaps, everyone on the planet.
In a dystopian future where all of humanity's memories have become government-regulated transactional products, mankind's crown-jewel memory is stolen - the answer to where we come from.
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