In the tradition of UNDERWORLD and DISTRICT 9, all of Manhattan is quarantined when the Lupine virus spreads like wildfire, turning innocent civilians into ravenous wolves. Nothing short of a nuclear blast can stop the monstrous virus.
When a group of scientists developing an engine for interstellar travel see their funding cut after a fatal disaster, the disgraced group must resort to criminal activity to finance their operation as they rebuild their space time device.